RNU6-108P

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, RNU6-108P RNA is linked to patient survival in 10 of 34 cancer types, making it the most broadly survival-associated RNU6-108P data layer.

The strongest signal is observed in thyroid carcinoma (THCA), where higher RNU6-108P RNA is associated with worse overall survival. In most high-consensus cancer types, elevated RNU6-108P expression acts as an unfavorable survival marker, although some lineages such as KIRP show a favorable association.

THCA, READ, and SKCM are the cancer types where RNU6-108P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
THCAOSTertileIV0.0950.966<.00172view →
READOSTertileII,III,IV0.1870.644.02336view →
SKCMOSTertileAll0.6150.787.02627view →
ACCOSTertileAll0.1410.706<.00118view →
SARCDFSTertileAll0.1060.353.02915view →
GBMOSTertileAll0.2130.432.0169view →
BLCADFSTertileIV0.1680.482.0239view →
COADOSTertileII,III,IV0.5140.796.0449view →
LUADDFSTertileAll0.3860.666.0219view →
KIRPDFSTertileAll1.0000.842.0373view →
Pink = unfavorable, green = favorable. Showing the 10 strongest of 10 lineages.

Exploration