RNU6-1089P

Across TCGA pan-cancer cohorts, RNU6-1089P RNA is linked to patient survival in 14 of 34 cancer types, making it the most broadly survival-associated RNU6-1089P data layer.

The strongest signal is observed in uterine carcinosarcoma (UCS), where higher RNU6-1089P RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated RNU6-1089P expression acts as an unfavorable survival marker, although some lineages such as OV and STAD show a favorable association.

UCS, THCA, and GBM are the cancer types where RNU6-1089P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCS	DFS	Tertile	II,III,IV	0.117	0.478	.001	72	view →
THCA	DFS	Tertile	II,III,IV	0.104	0.688	<.001	60	view →
GBM	OS	Tertile	All	0.132	0.433	.001	18	view →
LUSC	OS	Tertile	III,IV	0.054	0.768	<.001	18	view →
TGCT	DFS	Tertile	II,III,IV	0.088	0.917	.010	18	view →
PCPG	OS	Tertile	All	0.670	0.944	.030	18	view →
OV	DFS	Tertile	III,IV	0.625	0.517	.026	18	view →
STAD	DFS	Tertile	IV	0.520	0.250	.033	9	view →
LUAD	DFS	Tertile	All	0.603	0.328	.032	9	view →
HNSC	DFS	Tertile	All	0.122	0.360	.047	6	view →
UCEC	DFS	Tertile	All	0.391	0.654	.034	6	view →
ESCA	OS	Quartile	All	0.572	0.744	.014	4	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 14 lineages.

RNU6-1089P–UCS (DFS)

Open the UCS breakdown →