RNU6-1085P

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, RNU6-1085P RNA is linked to patient survival in 14 of 34 cancer types, making it the most broadly survival-associated RNU6-1085P data layer.

The strongest signal is observed in cholangiocarcinoma (CHOL), where higher RNU6-1085P RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated RNU6-1085P expression acts as an unfavorable survival marker, although some lineages such as COAD and BLCA show a favorable association.

CHOL, LUAD, and COAD are the cancer types where RNU6-1085P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
CHOLDFSTertileII,III,IV0.0160.406<.00172view →
LUADDFSTertileIV0.5320.978<.00163view →
COADDFSTertileIII,IV0.9600.628<.00157view →
UCSOSTertileII,III,IV0.1880.548.01454view →
BLCADFSTertileIV1.0000.446.00948view →
BRCADFSTertileAll0.5701.000.03336view →
ESCAOSTertileIV0.0950.512.00836view →
LUSCOSTertileIII,IV0.1980.581.00736view →
GBMOSTertileAll0.5220.337<.00127view →
SKCMOSTertileII,III,IV0.1730.381.00818view →
PAADDFSTertileAll0.5390.315.01618view →
DLBCDFSTertileIII,IV0.3830.984.04315view →
Pink = unfavorable, green = favorable. Showing the 12 strongest of 14 lineages.

Exploration