RNU6-1080P

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, RNU6-1080P RNA is linked to patient survival in 9 of 34 cancer types, making it the most broadly survival-associated RNU6-1080P data layer.

The strongest signal is observed in lung squamous cell carcinoma (LUSC), where higher RNU6-1080P RNA is associated with worse overall survival. In most high-consensus cancer types, elevated RNU6-1080P expression acts as an unfavorable survival marker, although some lineages such as ESCA show a favorable association.

LUSC, BRCA, and BLCA are the cancer types where RNU6-1080P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
LUSCOSTertileII,III,IV0.1000.780<.00172view →
BRCAOSTertileAll0.7560.925.00360view →
BLCADFSTertileAll0.1980.627.00954view →
THCADFSTertileIV0.1440.884<.00154view →
KIRCDFSTertileAll0.1820.634.00154view →
HNSCDFSTertileII,III,IV0.3190.616.01730view →
ESCADFSTertileIII,IV0.5870.259.03221view →
STADDFSTertileIV0.0830.379.0019view →
COADOSTertileII,III,IV0.2590.785.0449view →
Pink = unfavorable, green = favorable. Showing the 9 strongest of 9 lineages.

Exploration