RNU6-1075P

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, RNU6-1075P RNA is linked to patient survival in 5 of 34 cancer types, making it the most broadly survival-associated RNU6-1075P data layer.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher RNU6-1075P RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated RNU6-1075P expression acts as an unfavorable survival marker.

HNSC, LUSC, and LIHC are the cancer types where RNU6-1075P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
HNSCDFSTertileII,III,IV0.1800.558.01254view →
LUSCOSTertileAll0.0800.762<.00136view →
LIHCOSTertileAll0.0830.783<.00136view →
ESCAOSTertileAll0.1980.872.00336view →
SKCMDFSTertileAll0.0460.728<.0019view →
Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

Exploration