RNU6-1053P

Across TCGA pan-cancer cohorts, RNU6-1053P RNA is linked to patient survival in 23 of 34 cancer types, making it the most broadly survival-associated RNU6-1053P data layer.

The strongest signal is observed in adrenocortical carcinoma (ACC), where higher RNU6-1053P RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated RNU6-1053P expression acts as an unfavorable survival marker, although some lineages such as LAML and READ show a favorable association.

ACC, UVM, and LAML are the cancer types where RNU6-1053P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
ACC	DFS	Tertile	All	0.322	0.846	<.001	56	view →
UVM	DFS	Quartile	III,IV	0.224	0.723	.001	52	view →
LAML	DFS	Median	All	0.591	0.353	.001	38	view →
KICH	DFS	Tertile	II,III,IV	0.646	1.000	.007	37	view →
READ	OS	Tertile	II,III,IV	0.857	0.307	<.001	35	view →
MESO	DFS	Median	All	0.179	0.660	<.001	27	view →
CESC	DFS	Median	III,IV	0.210	0.648	.003	22	view →
LGG	DFS	Median	All	0.789	0.871	<.001	18	view →
UCEC	DFS	Median	II,III,IV	0.679	0.406	.029	16	view →
KIRC	DFS	Quartile	All	0.555	0.763	.016	15	view →
BRCA	OS	Tertile	III,IV	0.969	0.830	.007	13	view →
BLCA	OS	Median	II,III,IV	0.757	0.658	.012	13	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 23 lineages.

RNU6-1053P–ACC (DFS)

Open the ACC breakdown →