RNU6-1045P

Across TCGA pan-cancer cohorts, RNU6-1045P RNA is linked to patient survival in 15 of 34 cancer types, making it the most broadly survival-associated RNU6-1045P data layer.

The strongest signal is observed in uveal melanoma (UVM), where higher RNU6-1045P RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated RNU6-1045P expression acts as an unfavorable survival marker, although some lineages such as LIHC and BRCA show a favorable association.

UVM, KIRP, and CHOL are the cancer types where RNU6-1045P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UVM	DFS	Tertile	All	0.084	0.765	<.001	153	view →
KIRP	DFS	Tertile	All	0.185	0.631	<.001	60	view →
CHOL	OS	Tertile	II,III,IV	0.019	0.675	<.001	36	view →
THYM	DFS	Tertile	II,III,IV	0.172	0.747	.005	36	view →
TGCT	DFS	Tertile	II,III,IV	0.015	0.919	<.001	36	view →
BLCA	OS	Tertile	All	0.441	0.631	.018	36	view →
SKCM	OS	Tertile	III,IV	0.282	0.729	.003	24	view →
CESC	OS	Tertile	All	0.337	0.620	.004	24	view →
PRAD	DFS	Tertile	All	0.824	0.939	.011	18	view →
PAAD	OS	Tertile	II,III,IV	0.404	0.587	.018	9	view →
READ	OS	Tertile	III,IV	0.287	0.772	.030	9	view →
LIHC	DFS	Tertile	III,IV	0.486	0.159	.033	9	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 15 lineages.

RNU6-1045P–UVM (DFS)

Open the UVM breakdown →