Across TCGA pan-cancer cohorts, RNU6-103P RNA differs between tumor and matched normal tissue in 5 of 18 cancer types tested, making tumor–normal expression one of RNU6-103P’s most consistent transcriptional readouts.

The strongest signal is observed in lung adenocarcinoma (LUAD), where RNU6-103P RNA is repressed in tumor relative to normal tissue. In most cancer types RNU6-103P is over-expressed in tumor, although a few such as LUAD and ESCA show the opposite, repressed pattern.

LUAD, HNSC, and ESCA are the cancer types where RNU6-103P tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RNU6-103P RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LUAD	All	All	−0.467	<.001	7	view →
HNSC	All	All	+0.186	.007	3	view →
ESCA	Female	All	−0.643	.029	2	view →
PRAD	All	All	−0.292	.004	2	view →
KIRC	All	All	−0.047	.016	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 5 strongest of 5 lineages.

Exploration

Same gene, other analysis: RNU6-103P RNA expression & survival · all RNU6-103P data types