RNU6-1027P

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, RNU6-1027P RNA is linked to patient survival in 14 of 34 cancer types, making it the most broadly survival-associated RNU6-1027P data layer.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher RNU6-1027P RNA is associated with worse overall survival. In most high-consensus cancer types, elevated RNU6-1027P expression acts as an unfavorable survival marker, although some lineages such as ESCA and SKCM show a favorable association.

HNSC, KIRC, and CHOL are the cancer types where RNU6-1027P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
HNSCOSTertileII,III,IV0.0820.711<.00172view →
KIRCDFSTertileAll0.6380.877<.00142view →
CHOLDFSTertileAll0.0450.497.02936view →
LUADOSTertileIII,IV0.0830.680<.00136view →
THYMDFSTertileAll0.0910.884<.00127view →
BLCAOSTertileIII,IV0.1110.684<.00118view →
LIHCOSTertileAll0.2260.773.00818view →
TGCTDFSTertileIII,IV0.0170.923.02118view →
BRCADFSTertileII,III,IV0.7710.892.02612view →
SARCOSTertileAll0.4790.746.0479view →
ESCADFSTertileIII,IV0.5010.255.0466view →
LGGOSTertileAll0.6230.893.0066view →
Pink = unfavorable, green = favorable. Showing the 12 strongest of 14 lineages.

Exploration