RNU6-1025P

RNA — tumor vs normal
Tumor vs NormalRNABox plot · TCGA cohorts

Across TCGA pan-cancer cohorts, RNU6-1025P RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of RNU6-1025P’s most consistent transcriptional readouts.

The strongest signal is observed in breast invasive carcinoma (BRCA), where RNU6-1025P RNA is repressed in tumor relative to normal tissue. In most cancer types RNU6-1025P is over-expressed in tumor, although a few such as BRCA and THCA show the opposite, repressed pattern.

BRCA, STAD, and CHOL are the cancer types where RNU6-1025P tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RNU6-1025P RNA (log2); positive values indicate higher expression in tumor. p-values are from the differential-expression test.
LineageGenderStageFold-changepSampling consensus
BRCAAllIII,IV−0.172.0282view →
STADAllIII,IV+0.983.0201view →
CHOLAllAll+0.410.0321view →
THCAAllII,III,IV−0.153.0231view →
Pink = over-expressed in tumor, green = repressed in tumor. Showing the 4 strongest of 4 lineages.

Exploration