RNU6-101P

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, RNU6-101P RNA is linked to patient survival in 20 of 34 cancer types, making it the most broadly survival-associated RNU6-101P data layer.

The strongest signal is observed in uveal melanoma (UVM), where higher RNU6-101P RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated RNU6-101P expression acts as an unfavorable survival marker, although some lineages such as THCA and TGCT show a favorable association.

UVM, READ, and STAD are the cancer types where RNU6-101P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
UVMDFSTertileIII,IV0.2040.664.00160view →
READDFSTertileII,III,IV0.5490.828.00248view →
STADOSQuartileIII,IV0.4330.695.00236view →
PAADDFSTertileIII,IV0.1180.734.01436view →
OVOSQuartileIII,IV0.7810.850.00430view →
MESOOSTertileAll0.3810.572.03127view →
KIRCDFSTertileIV0.2130.502.04218view →
UCSOSTertileAll0.1850.686.03418view →
DLBCDFSTertileAll0.1080.711.03518view →
UCECDFSTertileIV0.2060.704.03318view →
PRADDFSTertileAll0.8270.901.02218view →
THCADFSMedianIV0.8650.499.01511view →
Pink = unfavorable, green = favorable. Showing the 12 strongest of 20 lineages.

Exploration