RNA, U6 small nuclear 1016, pseudogeneGenealiases: []
Q-omics provides the consensus-scored RNU6-1016P profile across patient tissues and cancer cell-line models. RNU6-1016P expression is associated with patient survival in 22 of 34 cancer types, with the highest sampling consensus in ACC. Among the 18 cancer types available for tumor–normal comparison, RNU6-1016P is differentially expressed in 10, with the highest sampling consensus in BRCA. Additionally, RNU6-1016P RNA expression shows 19,528 significant gene co-expression associations, with the highest sampling consensus in THYM. Together, these results highlight ACC, BRCA, and THYM as cancer lineages where RNU6-1016P shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for RNU6-1016P — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes RNU6-1016P survival associations across molecular data types. RNU6-1016P RNA expression shows survival associations in the most cancer types (22). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible RNU6-1016P RNA expression–survival associations across cancer types. High RNU6-1016P expression shows unfavorable associations in UVM, THCA and CHOL, but favorable associations in ACC, READ and HNSC. The ACC Kaplan–Meier curve shows clear separation, with the low-expression group declining faster, consistent with the favorable association (log-rank p = .005). Together, the overview and detailed table identify ACC as the clearest survival context for RNU6-1016P RNA expression.
This table summarizes RNU6-1016P tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 10. The strongest signals are observed in BRCA for RNA.
This table ranks reproducible tumor–normal expression differences for RNU6-1016P. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. RNU6-1016P shows lower tumor expression in BRCA, THCA and UCEC and higher tumor expression in KIRP, BLCA and KIRC. The BRCA box plot shows higher RNU6-1016P RNA expression in normal versus tumor tissue (log2 FC = −0.782, t-test p = .005).
This table shows molecular features associated with RNU6-1016P in patient tissues and cancer cell lines. In patient samples, RNU6-1016P shows the broadest associations at the RNA and protein expression levels, with THYM recurring as the lineage with the largest associated feature set.
