RNU6-1015P

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, RNU6-1015P RNA is linked to patient survival in 5 of 34 cancer types, making it the most broadly survival-associated RNU6-1015P data layer.

The strongest signal is observed in skin cutaneous melanoma (SKCM), where higher RNU6-1015P RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated RNU6-1015P expression acts as an unfavorable survival marker.

SKCM, UCEC, and STAD are the cancer types where RNU6-1015P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
SKCMDFSTertileAll0.0160.758<.00172view →
UCECDFSTertileAll0.6270.900<.00118view →
STADDFSTertileIV0.0830.379.0019view →
KIRPOSTertileAll0.7560.948.0289view →
BRCAOSTertileAll0.7800.963.0466view →
Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

RNU6-1015P–SKCM (DFS)

Kaplan–Meier survival curve for RNU6-1015P RNA-high vs -low samples in SKCM.

Open the SKCM breakdown →

Exploration