RNU6-1011P

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, RNU6-1011P RNA is linked to patient survival in 22 of 34 cancer types, making it the most broadly survival-associated RNU6-1011P data layer.

The strongest signal is observed in kidney renal papillary cell carcinoma (KIRP), where higher RNU6-1011P RNA is associated with worse overall survival. In most high-consensus cancer types, elevated RNU6-1011P expression acts as an unfavorable survival marker, although some lineages such as HNSC and SKCM show a favorable association.

KIRP, UVM, and KIRC are the cancer types where RNU6-1011P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
KIRPOSQuartileAll0.4140.803<.001116view →
UVMDFSTertileAll0.3370.734<.001102view →
KIRCDFSQuartileII,III,IV0.3880.674<.00166view →
ACCDFSMedianAll0.4240.727.00162view →
CESCOSMedianIII,IV0.6210.882.00238view →
HNSCDFSQuartileIII,IV0.7500.565.01735view →
LIHCOSTertileAll0.6000.786.00228view →
SKCMOSMedianIV0.8670.244.00627view →
LUSCDFSQuartileIII,IV0.1440.905.00326view →
UCSDFSTertileIV0.9360.364.02424view →
COADDFSTertileAll0.7390.844.00323view →
PAADDFSMedianII,III,IV0.5210.339.00719view →
Pink = unfavorable, green = favorable. Showing the 12 strongest of 22 lineages.

Exploration