RNU6-1010P

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, RNU6-1010P RNA is linked to patient survival in 21 of 34 cancer types, making it the most broadly survival-associated RNU6-1010P data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher RNU6-1010P RNA is associated with worse overall survival. In most high-consensus cancer types, elevated RNU6-1010P expression acts as an unfavorable survival marker, although some lineages such as PAAD and CESC show a favorable association.

KIRC, COAD, and THYM are the cancer types where RNU6-1010P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
KIRCOSMedianAll0.5240.723<.001132view →
COADOSTertileII,III,IV0.6640.830<.00168view →
THYMDFSQuartileIII,IV0.3530.921.00854view →
UVMDFSTertileAll0.4300.822.00348view →
PAADOSTertileAll0.5750.296.00530view →
CHOLDFSQuartileAll0.0960.510.00127view →
ACCOSQuartileAll0.3200.799.00227view →
CESCOSMedianAll0.9190.845.01822view →
LIHCDFSTertileAll0.4420.594.00518view →
LGGDFSTertileAll0.7360.852.00313view →
BRCAOSMedianAll0.9400.909.01212view →
MESOOSMedianAll0.3400.634.02412view →
Pink = unfavorable, green = favorable. Showing the 12 strongest of 21 lineages.

Exploration