RNU6-1004P

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, RNU6-1004P RNA is linked to patient survival in 16 of 34 cancer types, making it the most broadly survival-associated RNU6-1004P data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher RNU6-1004P RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated RNU6-1004P expression acts as an unfavorable survival marker, although some lineages such as CHOL and SARC show a favorable association.

KIRC, COAD, and KICH are the cancer types where RNU6-1004P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
KIRCDFSTertileAll0.4730.693<.001135view →
COADOSTertileIV0.1880.686<.00175view →
KICHDFSTertileII,III,IV0.1990.810<.00151view →
ACCDFSTertileIII,IV0.3120.573.01833view →
KIRPOSTertileAll0.8770.960.01018view →
LIHCOSTertileII,III,IV0.2920.635.00618view →
CHOLDFSTertileIII,IV1.0000.182.0349view →
HNSCOSTertileII,III,IV0.1450.425.0259view →
SARCDFSQuartileAll0.4850.245.0169view →
THYMOSMedianAll1.0000.655.0057view →
GBMOSMedianAll0.4300.229.0116view →
BRCAOSTertileIV0.3420.690.0436view →
Pink = unfavorable, green = favorable. Showing the 12 strongest of 16 lineages.

RNU6-1004P–KIRC (DFS)

Kaplan–Meier survival curve for RNU6-1004P RNA-high vs -low samples in KIRC.

Open the KIRC breakdown →

Exploration