RNU5F-8P

Across TCGA pan-cancer cohorts, RNU5F-8P RNA is linked to patient survival in 8 of 34 cancer types, making it the most broadly survival-associated RNU5F-8P data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher RNU5F-8P RNA is associated with worse overall survival. In most high-consensus cancer types, elevated RNU5F-8P expression acts as an unfavorable survival marker.

KIRC, LUSC, and LIHC are the cancer types where RNU5F-8P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	OS	Tertile	II,III,IV	0.163	0.535	.005	84	view →
LUSC	OS	Tertile	All	0.196	0.660	.009	36	view →
LIHC	DFS	Tertile	II,III,IV	0.109	0.431	.010	36	view →
COAD	OS	Tertile	All	0.210	0.801	.009	18	view →
SARC	OS	Tertile	All	0.032	0.861	<.001	18	view →
ACC	DFS	Tertile	II,III,IV	0.242	0.724	.034	18	view →
SKCM	OS	Tertile	II,III,IV	0.335	0.742	.013	9	view →
STAD	DFS	Tertile	IV	0.083	0.379	.001	9	view →

Pink = unfavorable, green = favorable. Showing the 8 strongest of 8 lineages.

RNU5F-8P–KIRC (OS)

Open the KIRC breakdown →