RNU5F-7P

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, RNU5F-7P RNA is linked to patient survival in 2 of 34 cancer types, making it the most broadly survival-associated RNU5F-7P data layer.

The strongest signal is observed in breast invasive carcinoma (BRCA), where higher RNU5F-7P RNA is associated with worse overall survival. In most high-consensus cancer types, elevated RNU5F-7P expression acts as an unfavorable survival marker, although some lineages such as ESCA show a favorable association.

BRCA and ESCA are the cancer types where RNU5F-7P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
BRCAOSTertileAll0.1680.579.04712view →
ESCAOSTertileIII,IV0.8020.368.03912view →
Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

Exploration