Across TCGA pan-cancer cohorts, RNU5F-7P RNA is linked to patient survival in 2 of 34 cancer types, making it the most broadly survival-associated RNU5F-7P data layer.
The strongest signal is observed in breast invasive carcinoma (BRCA), where higher RNU5F-7P RNA is associated with worse overall survival. In most high-consensus cancer types, elevated RNU5F-7P expression acts as an unfavorable survival marker, although some lineages such as ESCA show a favorable association.
BRCA and ESCA are the cancer types where RNU5F-7P RNA most reproducibly stratifies survival.