RNU5D-2P

Across TCGA pan-cancer cohorts, RNU5D-2P RNA is linked to patient survival in 6 of 34 cancer types, making it the most broadly survival-associated RNU5D-2P data layer.

The strongest signal is observed in lymphoid neoplasm diffuse large b-cell lymphoma (DLBC), where higher RNU5D-2P RNA is associated with worse overall survival. In most high-consensus cancer types, elevated RNU5D-2P expression acts as an unfavorable survival marker.

DLBC, THCA, and BRCA are the cancer types where RNU5D-2P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
DLBC	OS	Tertile	II,III,IV	0.172	0.949	<.001	90	view →
THCA	DFS	Tertile	II,III,IV	0.146	0.869	<.001	63	view →
BRCA	DFS	Tertile	All	0.664	0.903	.003	24	view →
UCEC	DFS	Tertile	III,IV	0.080	0.579	.045	18	view →
HNSC	OS	Tertile	III,IV	0.142	0.656	.010	9	view →
OV	OS	Tertile	All	0.710	0.844	.045	6	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

RNU5D-2P–DLBC (OS)

Open the DLBC breakdown →