RNU5A-7P

Across TCGA pan-cancer cohorts, RNU5A-7P RNA is linked to patient survival in 10 of 34 cancer types, making it the most broadly survival-associated RNU5A-7P data layer.

The strongest signal is observed in lymphoid neoplasm diffuse large b-cell lymphoma (DLBC), where higher RNU5A-7P RNA is associated with worse overall survival. In most high-consensus cancer types, elevated RNU5A-7P expression acts as an unfavorable survival marker, although some lineages such as KIRP and COAD show a favorable association.

DLBC, BLCA, and CHOL are the cancer types where RNU5A-7P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
DLBC	OS	Tertile	III,IV	0.249	0.965	<.001	126	view →
BLCA	OS	Tertile	All	0.172	0.608	<.001	72	view →
CHOL	DFS	Tertile	All	0.096	0.541	.003	72	view →
KIRP	DFS	Tertile	All	1.000	0.833	.006	48	view →
LIHC	DFS	Tertile	All	0.158	0.443	.011	24	view →
ESCA	OS	Tertile	All	0.508	0.719	.011	18	view →
GBM	OS	Tertile	All	0.217	0.424	.017	18	view →
COAD	DFS	Tertile	All	1.000	0.774	.020	9	view →
BRCA	OS	Tertile	II,III,IV	0.862	0.918	.036	6	view →
UCEC	DFS	Tertile	All	0.823	0.901	.040	6	view →

Pink = unfavorable, green = favorable. Showing the 10 strongest of 10 lineages.

RNU5A-7P–DLBC (OS)

Open the DLBC breakdown →