Across TCGA patient cohorts, RNU5A-2P RNA expression is significantly associated with the go_rna of many other GO terms, with 2,154 significant associations in total. LUSC shows the largest number of these associations.

The most reproducible RNU5A-2P-associated GO terms across cancer lineages are Regulation of alternative mRNA splicing, via spliceosome, Positive regulation of cold-induced thermogenesis, and Regulation of translation initiation in response to endoplasmic reticulum stress. Each is linked with RNU5A-2P in more than 4 cancer types. Because this analysis shows association rather than direction, both RNU5A-2P-to-partner and partner-to-RNU5A-2P results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RNU5A-2P→partner) and Y-score (partner→RNU5A-2P) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PAAD	Regulation of alternative mRNA splicing, via spliceosome →	+0.042	+0.073	<.001	.002	3	5
LUSC	Positive regulation of cold-induced thermogenesis →	+0.029	+0.082	<.001	.004	3	4
CESC	Regulation of translation initiation in response to endoplasmic reticulum stress →	+0.040	+0.045	.003	.001	3	4
PRAD	Phospholipid translocation →	+0.033	+0.027	.003	.003	2	5
THCA	Tooth mineralization →	+0.051	+0.037	<.001	<.001	3	4
CESC	Rac protein signal transduction →	+0.040	+0.051	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,154 associations by consensus.

Exploration

RNU5A-2P survival (RNA) · tumor vs normal (RNA) · all RNU5A-2P data types