Across TCGA pan-cancer cohorts, RNU4ATAC5P RNA is linked to patient survival in 6 of 34 cancer types, making it the most broadly survival-associated RNU4ATAC5P data layer.
The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher RNU4ATAC5P RNA is associated with worse overall survival. In most high-consensus cancer types, elevated RNU4ATAC5P expression acts as an unfavorable survival marker, although some lineages such as SKCM and BLCA show a favorable association.
KIRC, ACC, and THYM are the cancer types where RNU4ATAC5P RNA most reproducibly stratifies survival.
RNA survival associations by lineage
Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.