Across TCGA pan-cancer cohorts, RNU4ATAC11P RNA differs between tumor and matched normal tissue in 1 of 18 cancer types tested, making tumor–normal expression one of RNU4ATAC11P’s most consistent transcriptional readouts.
The strongest signal is observed in stomach adenocarcinoma (STAD), where RNU4ATAC11P RNA is more highly expressed in tumor relative to normal tissue. In most cancer types RNU4ATAC11P is over-expressed in tumor.
STAD are the cancer types where RNU4ATAC11P tumor–normal differential expression is most reproducible.