Q-omics provides the consensus-scored RNU4-91P profile across patient tissues and cancer cell-line models. RNU4-91P expression is associated with patient survival in 5 of 34 cancer types, with the highest sampling consensus in MESO. Additionally, RNU4-91P RNA expression shows 6,962 significant gene co-expression associations, with the highest sampling consensus in LUAD. Together, these results highlight MESO, and LUAD as cancer lineages where RNU4-91P shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.

Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.

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Survival associations

This table summarizes RNU4-91P survival associations across molecular data types. RNU4-91P RNA expression shows survival associations in the most cancer types (5). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.

RNU4-91P data type	Survival analysis	Lineage consensus	Lineage of highest sampling consensus
RNA	Kaplan–Meier	5	MESO (126)	view →

This table ranks reproducible RNU4-91P RNA expression–survival associations across cancer types. High RNU4-91P expression shows unfavorable associations in MESO, THCA, KIRC and UCEC, but favorable associations in LAML. The MESO Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify MESO as the clearest survival context for RNU4-91P RNA expression.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
MESO	OS	Tertile	III,IV	0.077	0.580	<.001	126	view →
THCA	OS	Tertile	II,III,IV	0.832	0.988	<.001	57	view →
LAML	DFS	Tertile	All	0.655	0.334	.020	18	view →
KIRC	DFS	Tertile	IV	0.127	0.630	.039	18	view →
UCEC	DFS	Tertile	All	0.388	0.653	.048	6	view →

Pink = unfavorable, green = favorable. all 5 lineages →

RNU4-91P-MESO (OS)

Kaplan–Meier survival curve for RNU4-91P RNA expression in MESO: high vs low expression groups.

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Cross-omics associations

This table shows molecular features associated with RNU4-91P in patient tissues and cancer cell lines. In patient samples, RNU4-91P shows the broadest associations at the RNA and protein expression levels, with LUAD recurring as the lineage with the largest associated feature set.

Associated data type	Strength (# associated data)	Lineage of highest associated data
▼RNA
RNA	6,962	LUAD (2586)	view →
Function (RNA)	5,716	STAD (4523)	view →