RNU4-89P

Across TCGA pan-cancer cohorts, RNU4-89P RNA is linked to patient survival in 21 of 34 cancer types, making it the most broadly survival-associated RNU4-89P data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher RNU4-89P RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated RNU4-89P expression acts as an unfavorable survival marker, although some lineages such as KIRP and LUSC show a favorable association.

KIRC, LIHC, and ACC are the cancer types where RNU4-89P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	DFS	Quartile	IV	0.171	0.502	<.001	111	view →
LIHC	OS	Quartile	II,III,IV	0.476	0.766	<.001	53	view →
ACC	OS	Quartile	All	0.626	0.948	.001	44	view →
KIRP	OS	Tertile	III,IV	0.655	0.151	.002	37	view →
PAAD	OS	Tertile	II,III,IV	0.463	0.651	.009	26	view →
LUSC	DFS	Median	II,III,IV	0.499	0.309	.015	24	view →
PRAD	OS	Median	All	0.987	1.000	.017	22	view →
READ	OS	Tertile	II,III,IV	0.939	0.332	.016	18	view →
SKCM	DFS	Tertile	III,IV	0.696	0.498	.003	16	view →
LGG	DFS	Median	All	0.659	0.842	<.001	15	view →
ESCA	DFS	Quartile	All	0.254	0.497	.006	9	view →
OV	OS	Median	IV	0.621	0.861	.019	8	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 21 lineages.

RNU4-89P–KIRC (DFS)

Open the KIRC breakdown →