Across TCGA pan-cancer cohorts, RNU4-86P RNA differs between tumor and matched normal tissue in 5 of 18 cancer types tested, making tumor–normal expression one of RNU4-86P’s most consistent transcriptional readouts.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where RNU4-86P RNA is more highly expressed in tumor relative to normal tissue. In most cancer types RNU4-86P is over-expressed in tumor, although a few such as THCA and STAD show the opposite, repressed pattern.

HNSC, CHOL, and THCA are the cancer types where RNU4-86P tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RNU4-86P RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
HNSC	All	II,III,IV	+0.043	.011	6	view →
CHOL	All	II,III,IV	+0.415	<.001	2	view →
THCA	Female	II,III,IV	−0.196	.012	2	view →
BRCA	All	III,IV	+0.088	.014	2	view →
STAD	Male	III,IV	−0.266	.025	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 5 strongest of 5 lineages.

Exploration

Same gene, other analysis: RNU4-86P RNA expression & survival · all RNU4-86P data types