RNU4-76P

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, RNU4-76P RNA is linked to patient survival in 6 of 34 cancer types, making it the most broadly survival-associated RNU4-76P data layer.

The strongest signal is observed in breast invasive carcinoma (BRCA), where higher RNU4-76P RNA is associated with worse overall survival. In most high-consensus cancer types, elevated RNU4-76P expression acts as an unfavorable survival marker.

BRCA, HNSC, and SKCM are the cancer types where RNU4-76P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
BRCAOSTertileIII,IV0.1240.833<.00172view →
HNSCDFSTertileII,III,IV0.1430.612.01136view →
SKCMDFSTertileIII,IV0.0580.648.00127view →
UCSDFSTertileAll0.1360.523.03418view →
SARCOSTertileAll0.1760.860<.00118view →
LGGOSTertileAll0.4150.811.0419view →
Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

Exploration