Across TCGA pan-cancer cohorts, RNU4-69P RNA is linked to patient survival in 3 of 34 cancer types, making it the most broadly survival-associated RNU4-69P data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher RNU4-69P RNA is associated with worse overall survival. In most high-consensus cancer types, elevated RNU4-69P expression acts as an unfavorable survival marker, although some lineages such as HNSC and LUSC show a favorable association.

KIRC, HNSC, and LUSC are the cancer types where RNU4-69P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	OS	Tertile	II,III,IV	0.169	0.567	<.001	90	view →
HNSC	OS	Tertile	IV	1.000	0.698	.044	3	view →
LUSC	DFS	Tertile	All	0.870	0.633	.045	3	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

Exploration

Same gene, other analysis: RNU4-69P tumor-vs-normal RNA expression · all RNU4-69P data types