RNU4-60P

Across TCGA pan-cancer cohorts, RNU4-60P RNA differs between tumor and matched normal tissue in 3 of 18 cancer types tested, making tumor–normal expression one of RNU4-60P’s most consistent transcriptional readouts.

The strongest signal is observed in stomach adenocarcinoma (STAD), where RNU4-60P RNA is more highly expressed in tumor relative to normal tissue. In most cancer types RNU4-60P is over-expressed in tumor, although a few such as ESCA show the opposite, repressed pattern.

STAD, LUSC, and ESCA are the cancer types where RNU4-60P tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RNU4-60P RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
STAD	Male	All	+0.198	.035	2	view →
LUSC	Male	II,III,IV	+0.161	.021	2	view →
ESCA	Female	All	−0.486	.020	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 3 strongest of 3 lineages.

RNU4-60P–STAD

Open the STAD breakdown →