Across TCGA pan-cancer cohorts, RNU4-59P RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of RNU4-59P’s most consistent transcriptional readouts.

The strongest signal is observed in stomach adenocarcinoma (STAD), where RNU4-59P RNA is more highly expressed in tumor relative to normal tissue. In most cancer types RNU4-59P is over-expressed in tumor.

STAD and BRCA are the cancer types where RNU4-59P tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RNU4-59P RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
STAD	All	All	+0.238	.019	2	view →
BRCA	Female	All	+0.138	.040	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 2 strongest of 2 lineages.

Exploration

Same gene, other analysis: RNU4-59P RNA expression & survival · all RNU4-59P data types