RNU4-57P

Across TCGA pan-cancer cohorts, RNU4-57P RNA is linked to patient survival in 11 of 34 cancer types, making it the most broadly survival-associated RNU4-57P data layer.

The strongest signal is observed in kidney chromophobe (KICH), where higher RNU4-57P RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated RNU4-57P expression acts as an unfavorable survival marker.

KICH, SKCM, and KIRP are the cancer types where RNU4-57P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KICH	DFS	Tertile	All	0.081	0.904	<.001	90	view →
SKCM	OS	Tertile	II,III,IV	0.187	0.737	<.001	63	view →
KIRP	DFS	Tertile	III,IV	0.082	0.451	.019	39	view →
STAD	OS	Tertile	IV	0.074	0.496	.002	36	view →
UCEC	DFS	Tertile	III,IV	0.167	0.706	<.001	36	view →
UVM	OS	Tertile	All	0.292	0.674	.035	18	view →
ACC	OS	Tertile	All	0.147	0.685	.018	18	view →
THCA	OS	Tertile	IV	0.720	1.000	.004	18	view →
DLBC	DFS	Tertile	III,IV	0.137	0.761	.014	9	view →
THYM	DFS	Tertile	II,III,IV	0.262	0.770	.032	6	view →
KIRC	DFS	Tertile	All	0.267	0.633	.033	6	view →

Pink = unfavorable, green = favorable. Showing the 11 strongest of 11 lineages.

RNU4-57P–KICH (DFS)

Open the KICH breakdown →