Across TCGA pan-cancer cohorts, RNU4-55P RNA is linked to patient survival in 3 of 34 cancer types, making it the most broadly survival-associated RNU4-55P data layer.
The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher RNU4-55P RNA is associated with worse overall survival. In most high-consensus cancer types, elevated RNU4-55P expression acts as an unfavorable survival marker, although some lineages such as LGG show a favorable association.
KIRC, STAD, and LGG are the cancer types where RNU4-55P RNA most reproducibly stratifies survival.