RNU4-29P

Across TCGA pan-cancer cohorts, RNU4-29P RNA differs between tumor and matched normal tissue in 6 of 18 cancer types tested, making tumor–normal expression one of RNU4-29P’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where RNU4-29P RNA is repressed in tumor relative to normal tissue. In most cancer types RNU4-29P is over-expressed in tumor, although a few such as KIRC and KICH show the opposite, repressed pattern.

KIRC, KICH, and CHOL are the cancer types where RNU4-29P tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RNU4-29P RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	All	IV	−0.593	<.001	12	view →
KICH	Male	All	−0.640	<.001	6	view →
CHOL	All	All	+0.657	.003	2	view →
PAAD	Female	All	−0.479	.041	2	view →
KIRP	All	All	−0.386	.014	1	view →
STAD	All	III,IV	+0.335	.028	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 6 strongest of 6 lineages.

RNU4-29P–KIRC

Open the KIRC breakdown →