RNU4-18P

Across TCGA pan-cancer cohorts, RNU4-18P RNA is linked to patient survival in 5 of 34 cancer types, making it the most broadly survival-associated RNU4-18P data layer.

The strongest signal is observed in bladder urothelial carcinoma (BLCA), where higher RNU4-18P RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated RNU4-18P expression acts as an unfavorable survival marker, although some lineages such as ESCA show a favorable association.

BLCA, SKCM, and SARC are the cancer types where RNU4-18P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
BLCA	DFS	Tertile	All	0.178	0.629	<.001	90	view →
SKCM	OS	Tertile	All	0.505	0.792	.004	27	view →
SARC	OS	Tertile	All	0.183	0.827	<.001	27	view →
ESCA	OS	Tertile	III,IV	0.829	0.358	.026	18	view →
STAD	DFS	Tertile	IV	0.083	0.379	.001	9	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

RNU4-18P–BLCA (DFS)

Open the BLCA breakdown →