RNU4-15P

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, RNU4-15P RNA is linked to patient survival in 12 of 34 cancer types, making it the most broadly survival-associated RNU4-15P data layer.

The strongest signal is observed in thyroid carcinoma (THCA), where higher RNU4-15P RNA is associated with worse overall survival. In most high-consensus cancer types, elevated RNU4-15P expression acts as an unfavorable survival marker.

THCA, STAD, and LIHC are the cancer types where RNU4-15P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
THCAOSTertileII,III,IV0.8640.981.00181view →
STADDFSTertileAll0.4630.576.01881view →
LIHCOSTertileAll0.0590.783<.00154view →
COADOSTertileIII,IV0.1880.709.00245view →
HNSCOSTertileIII,IV0.0840.681<.00145view →
ESCAOSTertileIV0.1350.568.03136view →
ACCDFSTertileII,III,IV0.2420.724.03418view →
PAADDFSTertileII,III,IV0.1260.452.00418view →
PRADOSTertileAll0.9470.995.00212view →
SARCOSTertileAll0.2140.766.0119view →
SKCMOSTertileAll0.1100.328.0046view →
DLBCDFSMedianIV0.1950.923.0385view →
Pink = unfavorable, green = favorable. Showing the 12 strongest of 12 lineages.

Exploration