RNU2-70P

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, RNU2-70P RNA is linked to patient survival in 15 of 34 cancer types, making it the most broadly survival-associated RNU2-70P data layer.

The strongest signal is observed in skin cutaneous melanoma (SKCM), where higher RNU2-70P RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated RNU2-70P expression acts as an unfavorable survival marker, although some lineages such as SKCM and LIHC show a favorable association.

SKCM, ACC, and READ are the cancer types where RNU2-70P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
SKCMDFSQuartileIII,IV0.5010.171.00154view →
ACCDFSTertileAll0.2330.615.01133view →
READOSTertileIII,IV0.5350.904.00224view →
CHOLOSTertileIII,IV0.2750.886.04518view →
KIRCDFSMedianIII,IV0.5560.702.02012view →
LIHCOSTertileAll0.8340.626.03512view →
LAMLDFSTertileAll0.5250.208.01410view →
PCPGDFSTertileAll0.3780.873.0059view →
THYMDFSTertileAll0.7850.896.0218view →
PAADDFSQuartileII,III,IV0.2890.465.0136view →
SARCOSTertileAll0.7630.482.0256view →
ESCAOSQuartileAll0.4550.628.0285view →
Pink = unfavorable, green = favorable. Showing the 12 strongest of 15 lineages.

Exploration