RNU2-56P

Across TCGA pan-cancer cohorts, RNU2-56P RNA is linked to patient survival in 8 of 34 cancer types, making it the most broadly survival-associated RNU2-56P data layer.

The strongest signal is observed in bladder urothelial carcinoma (BLCA), where higher RNU2-56P RNA is associated with worse overall survival. In most high-consensus cancer types, elevated RNU2-56P expression acts as an unfavorable survival marker, although some lineages such as HNSC show a favorable association.

BLCA, KIRC, and LIHC are the cancer types where RNU2-56P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
BLCA	OS	Tertile	III,IV	0.139	0.657	<.001	108	view →
KIRC	OS	Tertile	II,III,IV	0.127	0.806	<.001	54	view →
LIHC	OS	Tertile	II,III,IV	0.051	0.696	<.001	54	view →
KIRP	DFS	Tertile	All	0.218	0.771	.029	27	view →
CESC	DFS	Tertile	II,III,IV	0.281	0.710	.039	18	view →
COAD	OS	Tertile	II,III,IV	0.001	0.851	<.001	18	view →
UCS	DFS	Tertile	All	0.191	0.535	.029	18	view →
HNSC	DFS	Tertile	IV	0.727	0.524	.030	15	view →

Pink = unfavorable, green = favorable. Showing the 8 strongest of 8 lineages.

RNU2-56P–BLCA (OS)

Open the BLCA breakdown →