RNU2-53P

Across TCGA pan-cancer cohorts, RNU2-53P RNA is linked to patient survival in 5 of 34 cancer types, making it the most broadly survival-associated RNU2-53P data layer.

The strongest signal is observed in cervical squamous cell carcinoma and endocervical adenocarcinoma (CESC), where higher RNU2-53P RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated RNU2-53P expression acts as an unfavorable survival marker.

CESC, LIHC, and HNSC are the cancer types where RNU2-53P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CESC	DFS	Tertile	III,IV	0.053	0.729	<.001	72	view →
LIHC	OS	Tertile	All	0.127	0.710	<.001	72	view →
HNSC	OS	Tertile	II,III,IV	0.275	0.715	.008	63	view →
THCA	DFS	Tertile	II,III,IV	0.837	0.910	.021	24	view →
KIRC	OS	Tertile	All	0.815	0.888	.023	15	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

RNU2-53P–CESC (DFS)

Open the CESC breakdown →