RNU2-45P

Across TCGA pan-cancer cohorts, RNU2-45P RNA is linked to patient survival in 13 of 34 cancer types, making it the most broadly survival-associated RNU2-45P data layer.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher RNU2-45P RNA is associated with worse overall survival. In most high-consensus cancer types, elevated RNU2-45P expression acts as an unfavorable survival marker, although some lineages such as KIRC and BRCA show a favorable association.

UCEC, CESC, and LUAD are the cancer types where RNU2-45P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	OS	Tertile	II,III,IV	0.314	0.772	.014	36	view →
CESC	DFS	Tertile	All	0.259	0.746	.001	36	view →
LUAD	OS	Tertile	III,IV	0.153	0.660	.009	36	view →
PCPG	OS	Tertile	All	0.778	0.980	<.001	33	view →
SARC	OS	Tertile	All	0.162	0.527	<.001	33	view →
COAD	OS	Tertile	II,III,IV	0.273	0.792	.006	27	view →
KIRC	DFS	Tertile	IV	1.000	0.525	.023	24	view →
BRCA	OS	Tertile	II,III,IV	0.881	0.545	.039	21	view →
GBM	OS	Tertile	All	0.651	0.384	.008	18	view →
OV	DFS	Tertile	IV	0.174	0.474	.013	18	view →
BLCA	OS	Tertile	IV	0.176	0.603	.003	18	view →
THCA	DFS	Tertile	IV	0.463	0.896	.007	18	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 13 lineages.

RNU2-45P–UCEC (OS)

Open the UCEC breakdown →