Across TCGA pan-cancer cohorts, RNU2-40P RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of RNU2-40P’s most consistent transcriptional readouts.

The strongest signal is observed in lung squamous cell carcinoma (LUSC), where RNU2-40P RNA is more highly expressed in tumor relative to normal tissue. In most cancer types RNU2-40P is over-expressed in tumor, although a few such as THCA show the opposite, repressed pattern.

LUSC and THCA are the cancer types where RNU2-40P tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RNU2-40P RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LUSC	Male	All	+0.071	.015	2	view →
THCA	Female	II,III,IV	−0.146	.004	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 2 strongest of 2 lineages.

Exploration

Same gene, other analysis: RNU2-40P RNA expression & survival · all RNU2-40P data types