Across TCGA pan-cancer cohorts, RNU2-3P RNA differs between tumor and matched normal tissue in 3 of 18 cancer types tested, making tumor–normal expression one of RNU2-3P’s most consistent transcriptional readouts.

The strongest signal is observed in kidney chromophobe (KICH), where RNU2-3P RNA is repressed in tumor relative to normal tissue. In most cancer types RNU2-3P is over-expressed in tumor, although a few such as KICH and KIRC show the opposite, repressed pattern.

KICH, KIRC, and THCA are the cancer types where RNU2-3P tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RNU2-3P RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KICH	All	All	−0.187	.001	7	view →
KIRC	All	III,IV	−0.175	.002	6	view →
THCA	All	All	−0.026	.043	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 3 strongest of 3 lineages.

Exploration

Same gene, other analysis: RNU2-3P RNA expression & survival · all RNU2-3P data types