Across TCGA pan-cancer cohorts, RNU2-38P RNA differs between tumor and matched normal tissue in 3 of 18 cancer types tested, making tumor–normal expression one of RNU2-38P’s most consistent transcriptional readouts.

The strongest signal is observed in breast invasive carcinoma (BRCA), where RNU2-38P RNA is repressed in tumor relative to normal tissue. In most cancer types RNU2-38P is over-expressed in tumor, although a few such as BRCA and KIRC show the opposite, repressed pattern.

BRCA, KIRC, and COAD are the cancer types where RNU2-38P tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RNU2-38P RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
BRCA	Female	All	−0.198	.004	4	view →
KIRC	Female	III,IV	−0.323	.016	3	view →
COAD	Female	II,III,IV	−0.190	.045	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 3 strongest of 3 lineages.

Exploration

Same gene, other analysis: RNU2-38P RNA expression & survival · all RNU2-38P data types