RNU2-37P

RNA — tumor vs normal
Tumor vs NormalRNABox plot · TCGA cohorts

Across TCGA pan-cancer cohorts, RNU2-37P RNA differs between tumor and matched normal tissue in 5 of 18 cancer types tested, making tumor–normal expression one of RNU2-37P’s most consistent transcriptional readouts.

The strongest signal is observed in breast invasive carcinoma (BRCA), where RNU2-37P RNA is repressed in tumor relative to normal tissue. In most cancer types RNU2-37P is over-expressed in tumor, although a few such as BRCA and THCA show the opposite, repressed pattern.

BRCA, CHOL, and THCA are the cancer types where RNU2-37P tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RNU2-37P RNA (log2); positive values indicate higher expression in tumor. p-values are from the differential-expression test.
LineageGenderStageFold-changepSampling consensus
BRCAAllIV−0.540.0014view →
CHOLAllII,III,IV+0.495<.0012view →
THCAAllAll−0.101.0042view →
LUADAllIII,IV−0.191.0441view →
KICHAllAll−0.100.0201view →
Pink = over-expressed in tumor, green = repressed in tumor. Showing the 5 strongest of 5 lineages.

Exploration