Across TCGA pan-cancer cohorts, RNU2-33P RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of RNU2-33P’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where RNU2-33P RNA is repressed in tumor relative to normal tissue. In most cancer types RNU2-33P is over-expressed in tumor, although a few such as KIRC and COAD show the opposite, repressed pattern.

KIRC, UCEC, and COAD are the cancer types where RNU2-33P tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RNU2-33P RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	Female	All	−0.198	.012	5	view →
UCEC	All	All	+0.376	.001	4	view →
COAD	All	All	−0.317	.006	4	view →
HNSC	Male	All	+0.140	.005	4	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 4 strongest of 4 lineages.

Exploration

Same gene, other analysis: RNU2-33P RNA expression & survival · all RNU2-33P data types