RNU2-31P

Across TCGA pan-cancer cohorts, RNU2-31P RNA is linked to patient survival in 16 of 34 cancer types, making it the most broadly survival-associated RNU2-31P data layer.

The strongest signal is observed in bladder urothelial carcinoma (BLCA), where higher RNU2-31P RNA is associated with worse overall survival. In most high-consensus cancer types, elevated RNU2-31P expression acts as an unfavorable survival marker.

BLCA, TGCT, and THCA are the cancer types where RNU2-31P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
BLCA	OS	Tertile	All	0.535	0.723	<.001	78	view →
TGCT	OS	Tertile	II,III,IV	0.501	0.996	<.001	72	view →
THCA	OS	Tertile	III,IV	0.851	0.977	<.001	57	view →
MESO	OS	Tertile	All	0.332	0.567	.004	54	view →
READ	OS	Tertile	III,IV	0.555	0.902	.001	54	view →
UVM	OS	Tertile	All	0.220	0.917	<.001	54	view →
UCEC	OS	Tertile	All	0.875	0.928	.006	36	view →
KIRC	DFS	Tertile	All	0.429	0.670	.002	33	view →
DLBC	OS	Tertile	II,III,IV	0.118	0.802	.025	18	view →
KIRP	DFS	Tertile	III,IV	0.520	0.691	.008	18	view →
HNSC	DFS	Tertile	All	0.179	0.342	.016	18	view →
COAD	OS	Tertile	II,III,IV	0.657	0.854	.043	18	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 16 lineages.

RNU2-31P–BLCA (OS)

Open the BLCA breakdown →