Across TCGA pan-cancer cohorts, RNU2-24P RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of RNU2-24P’s most consistent transcriptional readouts.
The strongest signal is observed in stomach adenocarcinoma (STAD), where RNU2-24P RNA is more highly expressed in tumor relative to normal tissue. In most cancer types RNU2-24P is over-expressed in tumor.
STAD and UCEC are the cancer types where RNU2-24P tumor–normal differential expression is most reproducible.