Across TCGA pan-cancer cohorts, RNU2-21P RNA is linked to patient survival in 2 of 34 cancer types, making it the most broadly survival-associated RNU2-21P data layer.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher RNU2-21P RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated RNU2-21P expression acts as an unfavorable survival marker.

UCEC and STAD are the cancer types where RNU2-21P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	DFS	Tertile	All	0.588	0.844	<.001	18	view →
STAD	DFS	Tertile	All	0.284	0.717	.009	9	view →

Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

Exploration

Same gene, other analysis: RNU2-21P tumor-vs-normal RNA expression · all RNU2-21P data types