RNU2-20P

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, RNU2-20P RNA is linked to patient survival in 11 of 34 cancer types, making it the most broadly survival-associated RNU2-20P data layer.

The strongest signal is observed in stomach adenocarcinoma (STAD), where higher RNU2-20P RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated RNU2-20P expression acts as an unfavorable survival marker, although some lineages such as GBM show a favorable association.

STAD, LIHC, and SKCM are the cancer types where RNU2-20P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
STADDFSTertileAll0.4130.670<.001135view →
LIHCOSTertileII,III,IV0.2010.719.00254view →
SKCMDFSTertileAll0.1530.768<.00151view →
KIRPOSTertileIII,IV0.2840.821<.00145view →
LGGDFSTertileAll0.1470.408<.00136view →
PAADOSTertileII,III,IV0.2100.556.00736view →
SARCOSTertileAll0.1590.607<.00133view →
LUSCOSTertileII,III,IV0.3050.635.01727view →
GBMDFSTertileAll0.5430.194.02727view →
BLCADFSTertileAll0.0780.594<.00127view →
LUADDFSTertileIV0.6710.893.01912view →
Pink = unfavorable, green = favorable. Showing the 11 strongest of 11 lineages.

Exploration