RNU2-19P

Across TCGA pan-cancer cohorts, RNU2-19P RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of RNU2-19P’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where RNU2-19P RNA is repressed in tumor relative to normal tissue. In most cancer types RNU2-19P is over-expressed in tumor, although a few such as KIRC and KIRP show the opposite, repressed pattern.

KIRC, KIRP, and KICH are the cancer types where RNU2-19P tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RNU2-19P RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	Female	All	−0.581	<.001	11	view →
KIRP	All	All	−0.656	<.001	7	view →
KICH	All	All	−0.515	.002	2	view →
LUAD	All	All	+0.101	.032	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 4 strongest of 4 lineages.

RNU2-19P–KIRC

Open the KIRC breakdown →