RNU2-12P

Across TCGA pan-cancer cohorts, RNU2-12P RNA is linked to patient survival in 10 of 34 cancer types, making it the most broadly survival-associated RNU2-12P data layer.

The strongest signal is observed in bladder urothelial carcinoma (BLCA), where higher RNU2-12P RNA is associated with worse overall survival. In most high-consensus cancer types, elevated RNU2-12P expression acts as an unfavorable survival marker.

BLCA, HNSC, and KIRC are the cancer types where RNU2-12P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
BLCA	OS	Tertile	All	0.090	0.688	<.001	54	view →
HNSC	DFS	Tertile	II,III,IV	0.204	0.613	.027	45	view →
KIRC	DFS	Tertile	IV	0.127	0.619	.008	36	view →
LUSC	OS	Tertile	III,IV	0.011	0.684	<.001	36	view →
ESCA	OS	Tertile	All	0.198	0.872	.003	36	view →
SKCM	DFS	Tertile	All	0.170	0.737	.008	36	view →
DLBC	OS	Tertile	III,IV	0.175	0.874	.025	27	view →
OV	OS	Tertile	IV	0.233	0.633	.025	18	view →
THCA	DFS	Tertile	All	0.556	0.909	.018	18	view →
UCEC	OS	Tertile	All	0.895	0.927	.048	6	view →

Pink = unfavorable, green = favorable. Showing the 10 strongest of 10 lineages.

RNU2-12P–BLCA (OS)

Open the BLCA breakdown →